Autoimmune pancreatitis and extrapancreatic manifestations of IgG4-related sclerosing disease
| Journal | Volume 73 - 2010 |
| Issue | Fasc.2 - Case series |
| Author(s) | W. Van Moerkercke, M. Verhamme, P. Doubel, G. Meeus, R. Oyen, W. Van Steenbergen |
| Full article |
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| (1) Department of Gastroenterology and Hepatology, (4) Department of Radiology, (5) Department of Hepatology, University Hospitals Leuven, Leuven ; (2) Department of Gastroenterology and Hepatology, (3) Department of Nephrology, AZ Groeninge Kortrijk, Kortrijk. |
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In a review of the literature concerning autoimmune pancreati- tis we had special interest for the concept of IgG4-related pa- thology as a systemic disease with several clinical manifestations. In general, IgG4-positivity can not only be found in the pancreas, but also at the level of the kidneys, extrahepatic biliary ducts, gall- bladder, lungs, salivary glands, lacrimal glands, retroperitoneal tissue, ureters, prostate, meninges and lymph nodes. IgG4 seems to be a central key player in the pathophysiology of this disease. (Acta gastroenterol. belg., 2010, 73, 239-246). |
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© Acta Gastro-Enterologica Belgica. PMID 20690563 |
